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What is the most important information I should know about methadone?
• When methadone is used as part of a treatment program for narcotic addictionmaintenance or detoxification, it must be dispensed by a specially approvedpharmacy pain methadone.
• Use caution when driving, operating machinery, or performing other hazardousactivities pain methadone. Methadone may cause dizziness or drowsiness pain methadone. If you experience dizzinessor drowsiness, avoid these activities pain methadone.


What is methadone?
• Methadone is a narcotic pain reliever, similar to morphine pain methadone. Methadonealso reduces withdrawal symptoms in people addicted to heroin or other narcoticdrugs without causing the '"high" associated with the drug addiction pain methadone.
• Methadone is used as a pain reliever and as part of drug addiction detoxificationand maintenance programs pain methadone.
• Methadone may also be used for purposes other than those listed here pain methadone.


What should I discuss with my healthcare provider before taking methadone?
• Before taking methadone, talk to your doctor if you have
· kidney disease;
· liver disease;
· asthma, lung disease, or breathing problems;
· an enlarged prostate or difficulty urinating;
· hypothyroidism;
· seizures or epilepsy;
· a head injury or brain tumor; or
· Addison's disease pain methadone.
• You may not be able to take methadone, or you may require a dosage adjustmentor special monitoring during treatment pain methadone.
• Do not take methadone without first talking to your doctor if you arepregnant or could become pregnant during treatment pain methadone.
• Do not take methadone without first talking to your doctor if you arebreast-feeding a baby pain methadone.


How should I take methadone?
• Take methadone exactly as directed by your doctor pain methadone. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you pain methadone.
• When methadone is used as part of a treatment program for narcotic addictionmaintenance or detoxification, it must be dispensed by a specially approvedpharmacy pain methadone.
• Methadone is available as tablets, liquid for oral administration, andas an injection pain methadone. Oral forms of methadone must never be injected pain methadone.
• Take the oral tablets with a full glass of water pain methadone.
• To ensure that you get a correct dose, measure the liquid with a dose-measuringspoon, dropper, or cup, not a regular table spoon pain methadone. If you do not have a dose-measuringdevice, ask your pharmacist where you can get one pain methadone.
• Your healthcare provider may recommend that methadone be administeredby a family member, friend, or healthcare provider to ensure compliance withthe treatment pain methadone.
• Do not take more methadone than is prescribed pain methadone. If you symptoms are notbeing adequately treated, contact your healthcare provider pain methadone.
• It is important to take methadone regularly to get the most benefit pain methadone.
• Additional forms of counseling and/or monitoring may be recommended duringtreatment with methadone pain methadone.
• Methadone may be habit forming pain methadone. Physical and/or psychological dependencecan occur, and withdrawal effects are possible if the medication is stoppedsuddenly after prolonged or high-dose treatment pain methadone. Do not stop taking methadonesuddenly without first talking to your doctor if you have been taking it ona regular basis pain methadone. Your healthcare provider may want to gradually reduce the dose pain methadone.
• Store methadone at room temperature away from moisture and heat pain methadone.


What happens if I miss a dose?
• Take the missed dose as soon as you remember pain methadone. If it is almost time forthe next dose, skip the missed dose and take only the next regularly scheduleddose pain methadone. Do not take a double dose of the medication pain methadone.


What happens if I overdose?
• Seek emergency medical attention if an overdose of methadone is suspected pain methadone.
• Symptoms of a methadone overdose may include shallow or decreased breathing,slow heart rate, small pupils, cold, clammy skin, coma, and death pain methadone.


What should I avoid while using methadone?
• Use caution when driving, operating machinery, or performing other hazardousactivities pain methadone. Methadone may cause dizziness or drowsiness pain methadone. If you experience dizzinessor drowsiness, avoid these activities pain methadone.
• Do not take any prescription or over-the-counter medicine to treat acold, cough, or pain while taking methadone without first talking to your doctor pain methadone. These medicines may contain narcotics or alcohol pain methadone.
• Do not use narcotic drugs or alcohol while taking methadone pain methadone.
• Do not take more methadone than is prescribed pain methadone. If you symptoms are notbeing adequately treated, contact your healthcare provider pain methadone.


What are the possible side effects of methadone?
• If you experience any of the following serious side effects, stop takingmethadone and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· difficulty breathing;
· hallucinations or confusion;
· chest pain;
· fainting; or
· loss of consciousness pain methadone.
• Other, less serious side effects may be more likely to occur pain methadone. Continueto take methadone and talk to your doctor if you experience
· anxiety, nervousness, or restlessness;
· dizziness or lightheadedness;
· nausea, vomiting, or diarrhea;
· drowsiness;
· decreased appetite;
· dry mouth;
· constipation;
· weakness; or
· sexual problems pain methadone.
• Methadone may be habit forming pain methadone. Physical and/or psychological dependencecan occur, and withdrawal effects are possible if the medication is stoppedsuddenly after prolonged or high-dose treatment pain methadone. Do not stop taking methadonesuddenly without first talking to your doctor if you have been taking it ona regular basis pain methadone. Your healthcare provider may want to gradually reduce the dose pain methadone.
• Side effects other than those listed here may also occur pain methadone. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome pain methadone.


What other drugs will affect methadone?
• Do not take methadone with any of the following drugs without first talkingto your doctor:
· a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan),phenelzine (Nardil), tranylcypromine (Parnate);
· rifampin (Rifadin, Rimactane); or
· a narcotic pain reliever such as buprenorphine (Buprenex, Subutrex),codeine (Tylenol with Codeine, others), hydrocodone (Lorcet, Lortab, Vicodin,Vicoprofen, others), hydromorphone (Dilaudid), levorphanol (Levo-Dromoran),meperidine (Demerol), morphine (Kadian, MS Contin, MSIR, OMS, Roxanol, OramorphSR, others), oxycodone (M-Oxy, OxyContin, OxyIR, Roxicodone, Percocet, Percodan,others), oxymorphone (Numorphan), propoxyphene (Darvon, Darvocet, others), andothers pain methadone.
• You may not be able to take methadone, or you may require a dosage adjustmentor special monitoring during treatment pain methadone.
• Methadone may increase the effects of other drugs that cause drowsinessor dizziness, including antidepressants, alcohol, sedatives (used to treat insomnia),pain relievers, anxiety medicines, muscle relaxants, and antihistamines pain methadone. Donot drink alcohol and do not take any medicine without first talking to yourdoctor while taking methadone pain methadone.
• Do not take any prescription or over-the-counter medicine to treat acold, cough, or pain while taking methadone without first talking to your doctor pain methadone. These medicines may contain narcotics or alcohol pain methadone.
• Drugs other than those listed here may also interact with methadone pain methadone. Talk to your healthcare provider before taking any other prescription or over-the-countermedicines, including vitamins, minerals, and herbal products pain methadone.


Where can I get more information?
• Your pharmacist has additional information about methadone written forhealth professionals that you may read pain methadone.


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