hair loss with methotrexate
(meth oh TREX ate)
Dose Pack, Trexall
What is the most important information I should know about methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication hair loss with methotrexate.
• Methotrexate may cause side effects that could be dangerous or life-threatening hair loss with methotrexate. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment hair loss with methotrexate. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain, sores in or aroundthe mouth); liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others hair loss with methotrexate. Notify your doctor immediately if you develop any of these symptoms hair loss with methotrexate.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment hair loss with methotrexate. Methotrexate is in the FDA pregnancy category X hair loss with methotrexate. This meansthat it is known to cause birth defects in an unborn baby hair loss with methotrexate. Methotrexate canaffect a baby both when a woman is treated and when a man is treated hair loss with methotrexate. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment hair loss with methotrexate. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment hair loss with methotrexate.
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor hair loss with methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects hair loss with methotrexate. Discuss the use of aspirin and NSAIDs with yourdoctor hair loss with methotrexate.
• Do not drink alcohol while taking methotrexate hair loss with methotrexate.
What is methotrexate?
• Methotrexate interferes with the production and maintenance of DNA, whichis the genetic material in the cells of the body hair loss with methotrexate. Methotrexate has a greatereffect on cells that reproduce often such as cancer cells, bone marrow cells,skin cells, and others hair loss with methotrexate. This is how methotrexate works in the treatment of cancerand psoriasis hair loss with methotrexate. It is not known exactly how methotrexate works in the treatmentof rheumatoid arthritis hair loss with methotrexate.
• Methotrexate is used to treat certain types of cancer, psoriasis, andrheumatoid arthritis hair loss with methotrexate.
• Methotrexate may also be used for purposes other than those listed inthis medication guide hair loss with methotrexate.
What should I discuss with my healthcare provider before taking methotrexate?
• Before taking methotrexate, tell your doctor if you have
· liver disease or a history of liver problems;
· kidney disease;
· alcoholism or alcoholic liver disease;
· an immune system disorder;
· blood or bone marrow problems;
· an infection;
· a stomach ulcer;
· ulcerative colitis;
· diabetes;
· fluid around the lungs or in the abdomen; or
· asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis,or any other lung disease hair loss with methotrexate.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring during therapy if you have any of the conditionslisted above hair loss with methotrexate.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment hair loss with methotrexate. Methotrexate is in the FDA pregnancy category X hair loss with methotrexate. This meansthat it is known to cause birth defects in an unborn baby hair loss with methotrexate. Methotrexate canaffect a baby both when a woman is treated and when a man is treated hair loss with methotrexate. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment hair loss with methotrexate. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment hair loss with methotrexate.
• Methotrexate may be harmful to a nursing infant hair loss with methotrexate. Breast-feeding is notrecommended during treatment with methotrexate hair loss with methotrexate.
How should I take methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication hair loss with methotrexate.
• Take oral methotrexate exactly as directed by your doctor hair loss with methotrexate. If you donot understand these instructions, ask your pharmacist, nurse, or doctor toexplain them to you hair loss with methotrexate.
• Take each oral dose with a full glass of water hair loss with methotrexate.
• Methotrexate is also available as an injection hair loss with methotrexate. If you are using injectablemethotrexate at home, your doctor will give you detailed instructions regardingpreparation, administration, and storage of the medication hair loss with methotrexate.
• Do not take more of this medication than is prescribed hair loss with methotrexate. Too much methotrexatecan be dangerous, possibly resulting in death hair loss with methotrexate. Methotrexate is used to treatdifferent medical conditions, each with a different dosing regimen hair loss with methotrexate. Follow yourdoctor's instructions hair loss with methotrexate.
• It is important to take methotrexate regularly to get the most benefit hair loss with methotrexate.
• Your doctor may want you to have blood tests or other medical evaluationsduring treatment with methotrexate to monitor progress and side effects hair loss with methotrexate.
• Store methotrexate at room temperature away from moisture and heat hair loss with methotrexate.
What happens if I miss a dose?
• Contact your doctor if you miss a dose of methotrexate hair loss with methotrexate.
What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected hair loss with methotrexate.
• Symptoms of a methotrexate overdose may include nausea, vomiting, bleedingin the stomach, sores in the mouth, blood and bone marrow problems, and possiblydeath hair loss with methotrexate.
What should I avoid while taking methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor hair loss with methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects hair loss with methotrexate. Discuss the use of aspirin and NSAIDs with yourdoctor hair loss with methotrexate.
• Do not drink alcohol while taking methotrexate hair loss with methotrexate.
• Avoid prolonged exposure to sunlight hair loss with methotrexate. Methotrexate may increase the sensitivityof the skin to sunlight hair loss with methotrexate. Use a sunscreen and wear protective clothing when exposureto the sun is unavoidable hair loss with methotrexate.
What are the possible side effects of methotrexate?
• Methotrexate may cause side effects that could be dangerous or life-threatening hair loss with methotrexate. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment hair loss with methotrexate. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain); sores in or aroundthe mouth; liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others hair loss with methotrexate. Notify your doctor immediately if you develop any of these symptoms hair loss with methotrexate.
• If you experience any of the following serious side effects, seek emergencymedical attention or contact your doctor immediately:
· an allergic reaction (shortness of breath; closing of the throat; difficultybreathing; swelling of the lips, face, or tongue; or hives);
· joint pain; or
· confusion, unusual behavior, or seizures hair loss with methotrexate.
• Other, less serious side effects may be more likely to occur hair loss with methotrexate. Continueto take methotrexate and notify your doctor if you experience
· nausea, vomiting, or decreased appetite;
· itching or a skin rash;
· hair loss;
· boils or acne;
· dizziness;
· increased sensitivity of the skin to sunlight;
· headache;
· drowsiness; or
· blurred vision hair loss with methotrexate.
• Side effects other than those listed here may also occur hair loss with methotrexate. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome hair loss with methotrexate.
What other drugs will affect methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor hair loss with methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects hair loss with methotrexate.
• Before taking methotrexate, tell your doctor if you are taking any ofthe following medicines:
· etretinate (Tegison);
· acitretin (Soriatane);
· theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin,others);
· phenytoin (Dilantin);
· probenecid (Benemid);
· procarbazine (Matulane);
· folic acid or a vitamin supplement that contains folic acid;
· a penicillin antibiotic such as ampicillin (Principen, others), amoxicillin(Amoxil, Trimox, Augmentin, others), dicloxacillin (Dynapen, others), penicillin(Pen-Vee-K, Veetids, others), and others;
· a tetracycline antibiotic such as minocycline (Minocin, Dynacin, others),doxycycline (Vibramycin, Vibra-Tabs, others), tetracycline (Sumycin, others),and others; or
· a sulfa-based medicine such as sulfamethoxazole (Bactrim, Septra, Sulfatrim,Gantanol), sulfisoxazole (Gantrisin), and others hair loss with methotrexate.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring if you are taking any of the medicines listedabove hair loss with methotrexate.
• Drugs other than those listed here may also interact with methotrexate hair loss with methotrexate. Talk to your doctor and pharmacist before taking any prescription or over-the-countermedicines, including vitamins, minerals, and herbal products hair loss with methotrexate.
Where can I get more information?
• Your pharmacist has additional information about methotrexate writtenfor health professionals that you may read hair loss with methotrexate.
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