methotrexate gyn uses
(meth oh TREX ate)
Dose Pack, Trexall
What is the most important information I should know about methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication methotrexate gyn uses.
• Methotrexate may cause side effects that could be dangerous or life-threatening methotrexate gyn uses. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment methotrexate gyn uses. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain, sores in or aroundthe mouth); liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others methotrexate gyn uses. Notify your doctor immediately if you develop any of these symptoms methotrexate gyn uses.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment methotrexate gyn uses. Methotrexate is in the FDA pregnancy category X methotrexate gyn uses. This meansthat it is known to cause birth defects in an unborn baby methotrexate gyn uses. Methotrexate canaffect a baby both when a woman is treated and when a man is treated methotrexate gyn uses. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment methotrexate gyn uses. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment methotrexate gyn uses.
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor methotrexate gyn uses. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects methotrexate gyn uses. Discuss the use of aspirin and NSAIDs with yourdoctor methotrexate gyn uses.
• Do not drink alcohol while taking methotrexate methotrexate gyn uses.
What is methotrexate?
• Methotrexate interferes with the production and maintenance of DNA, whichis the genetic material in the cells of the body methotrexate gyn uses. Methotrexate has a greatereffect on cells that reproduce often such as cancer cells, bone marrow cells,skin cells, and others methotrexate gyn uses. This is how methotrexate works in the treatment of cancerand psoriasis methotrexate gyn uses. It is not known exactly how methotrexate works in the treatmentof rheumatoid arthritis methotrexate gyn uses.
• Methotrexate is used to treat certain types of cancer, psoriasis, andrheumatoid arthritis methotrexate gyn uses.
• Methotrexate may also be used for purposes other than those listed inthis medication guide methotrexate gyn uses.
What should I discuss with my healthcare provider before taking methotrexate?
• Before taking methotrexate, tell your doctor if you have
· liver disease or a history of liver problems;
· kidney disease;
· alcoholism or alcoholic liver disease;
· an immune system disorder;
· blood or bone marrow problems;
· an infection;
· a stomach ulcer;
· ulcerative colitis;
· diabetes;
· fluid around the lungs or in the abdomen; or
· asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis,or any other lung disease methotrexate gyn uses.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring during therapy if you have any of the conditionslisted above methotrexate gyn uses.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment methotrexate gyn uses. Methotrexate is in the FDA pregnancy category X methotrexate gyn uses. This meansthat it is known to cause birth defects in an unborn baby methotrexate gyn uses. Methotrexate canaffect a baby both when a woman is treated and when a man is treated methotrexate gyn uses. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment methotrexate gyn uses. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment methotrexate gyn uses.
• Methotrexate may be harmful to a nursing infant methotrexate gyn uses. Breast-feeding is notrecommended during treatment with methotrexate methotrexate gyn uses.
How should I take methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication methotrexate gyn uses.
• Take oral methotrexate exactly as directed by your doctor methotrexate gyn uses. If you donot understand these instructions, ask your pharmacist, nurse, or doctor toexplain them to you methotrexate gyn uses.
• Take each oral dose with a full glass of water methotrexate gyn uses.
• Methotrexate is also available as an injection methotrexate gyn uses. If you are using injectablemethotrexate at home, your doctor will give you detailed instructions regardingpreparation, administration, and storage of the medication methotrexate gyn uses.
• Do not take more of this medication than is prescribed methotrexate gyn uses. Too much methotrexatecan be dangerous, possibly resulting in death methotrexate gyn uses. Methotrexate is used to treatdifferent medical conditions, each with a different dosing regimen methotrexate gyn uses. Follow yourdoctor's instructions methotrexate gyn uses.
• It is important to take methotrexate regularly to get the most benefit methotrexate gyn uses.
• Your doctor may want you to have blood tests or other medical evaluationsduring treatment with methotrexate to monitor progress and side effects methotrexate gyn uses.
• Store methotrexate at room temperature away from moisture and heat methotrexate gyn uses.
What happens if I miss a dose?
• Contact your doctor if you miss a dose of methotrexate methotrexate gyn uses.
What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected methotrexate gyn uses.
• Symptoms of a methotrexate overdose may include nausea, vomiting, bleedingin the stomach, sores in the mouth, blood and bone marrow problems, and possiblydeath methotrexate gyn uses.
What should I avoid while taking methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor methotrexate gyn uses. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects methotrexate gyn uses. Discuss the use of aspirin and NSAIDs with yourdoctor methotrexate gyn uses.
• Do not drink alcohol while taking methotrexate methotrexate gyn uses.
• Avoid prolonged exposure to sunlight methotrexate gyn uses. Methotrexate may increase the sensitivityof the skin to sunlight methotrexate gyn uses. Use a sunscreen and wear protective clothing when exposureto the sun is unavoidable methotrexate gyn uses.
What are the possible side effects of methotrexate?
• Methotrexate may cause side effects that could be dangerous or life-threatening methotrexate gyn uses. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment methotrexate gyn uses. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain); sores in or aroundthe mouth; liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others methotrexate gyn uses. Notify your doctor immediately if you develop any of these symptoms methotrexate gyn uses.
• If you experience any of the following serious side effects, seek emergencymedical attention or contact your doctor immediately:
· an allergic reaction (shortness of breath; closing of the throat; difficultybreathing; swelling of the lips, face, or tongue; or hives);
· joint pain; or
· confusion, unusual behavior, or seizures methotrexate gyn uses.
• Other, less serious side effects may be more likely to occur methotrexate gyn uses. Continueto take methotrexate and notify your doctor if you experience
· nausea, vomiting, or decreased appetite;
· itching or a skin rash;
· hair loss;
· boils or acne;
· dizziness;
· increased sensitivity of the skin to sunlight;
· headache;
· drowsiness; or
· blurred vision methotrexate gyn uses.
• Side effects other than those listed here may also occur methotrexate gyn uses. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome methotrexate gyn uses.
What other drugs will affect methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor methotrexate gyn uses. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects methotrexate gyn uses.
• Before taking methotrexate, tell your doctor if you are taking any ofthe following medicines:
· etretinate (Tegison);
· acitretin (Soriatane);
· theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin,others);
· phenytoin (Dilantin);
· probenecid (Benemid);
· procarbazine (Matulane);
· folic acid or a vitamin supplement that contains folic acid;
· a penicillin antibiotic such as ampicillin (Principen, others), amoxicillin(Amoxil, Trimox, Augmentin, others), dicloxacillin (Dynapen, others), penicillin(Pen-Vee-K, Veetids, others), and others;
· a tetracycline antibiotic such as minocycline (Minocin, Dynacin, others),doxycycline (Vibramycin, Vibra-Tabs, others), tetracycline (Sumycin, others),and others; or
· a sulfa-based medicine such as sulfamethoxazole (Bactrim, Septra, Sulfatrim,Gantanol), sulfisoxazole (Gantrisin), and others methotrexate gyn uses.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring if you are taking any of the medicines listedabove methotrexate gyn uses.
• Drugs other than those listed here may also interact with methotrexate methotrexate gyn uses. Talk to your doctor and pharmacist before taking any prescription or over-the-countermedicines, including vitamins, minerals, and herbal products methotrexate gyn uses.
Where can I get more information?
• Your pharmacist has additional information about methotrexate writtenfor health professionals that you may read methotrexate gyn uses.
|
