placenta accreta methotrexate
(meth oh TREX ate)
Dose Pack, Trexall
What is the most important information I should know about methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication placenta accreta methotrexate.
• Methotrexate may cause side effects that could be dangerous or life-threatening placenta accreta methotrexate. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment placenta accreta methotrexate. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain, sores in or aroundthe mouth); liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others placenta accreta methotrexate. Notify your doctor immediately if you develop any of these symptoms placenta accreta methotrexate.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment placenta accreta methotrexate. Methotrexate is in the FDA pregnancy category X placenta accreta methotrexate. This meansthat it is known to cause birth defects in an unborn baby placenta accreta methotrexate. Methotrexate canaffect a baby both when a woman is treated and when a man is treated placenta accreta methotrexate. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment placenta accreta methotrexate. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment placenta accreta methotrexate.
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor placenta accreta methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects placenta accreta methotrexate. Discuss the use of aspirin and NSAIDs with yourdoctor placenta accreta methotrexate.
• Do not drink alcohol while taking methotrexate placenta accreta methotrexate.
What is methotrexate?
• Methotrexate interferes with the production and maintenance of DNA, whichis the genetic material in the cells of the body placenta accreta methotrexate. Methotrexate has a greatereffect on cells that reproduce often such as cancer cells, bone marrow cells,skin cells, and others placenta accreta methotrexate. This is how methotrexate works in the treatment of cancerand psoriasis placenta accreta methotrexate. It is not known exactly how methotrexate works in the treatmentof rheumatoid arthritis placenta accreta methotrexate.
• Methotrexate is used to treat certain types of cancer, psoriasis, andrheumatoid arthritis placenta accreta methotrexate.
• Methotrexate may also be used for purposes other than those listed inthis medication guide placenta accreta methotrexate.
What should I discuss with my healthcare provider before taking methotrexate?
• Before taking methotrexate, tell your doctor if you have
· liver disease or a history of liver problems;
· kidney disease;
· alcoholism or alcoholic liver disease;
· an immune system disorder;
· blood or bone marrow problems;
· an infection;
· a stomach ulcer;
· ulcerative colitis;
· diabetes;
· fluid around the lungs or in the abdomen; or
· asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis,or any other lung disease placenta accreta methotrexate.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring during therapy if you have any of the conditionslisted above placenta accreta methotrexate.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment placenta accreta methotrexate. Methotrexate is in the FDA pregnancy category X placenta accreta methotrexate. This meansthat it is known to cause birth defects in an unborn baby placenta accreta methotrexate. Methotrexate canaffect a baby both when a woman is treated and when a man is treated placenta accreta methotrexate. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment placenta accreta methotrexate. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment placenta accreta methotrexate.
• Methotrexate may be harmful to a nursing infant placenta accreta methotrexate. Breast-feeding is notrecommended during treatment with methotrexate placenta accreta methotrexate.
How should I take methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication placenta accreta methotrexate.
• Take oral methotrexate exactly as directed by your doctor placenta accreta methotrexate. If you donot understand these instructions, ask your pharmacist, nurse, or doctor toexplain them to you placenta accreta methotrexate.
• Take each oral dose with a full glass of water placenta accreta methotrexate.
• Methotrexate is also available as an injection placenta accreta methotrexate. If you are using injectablemethotrexate at home, your doctor will give you detailed instructions regardingpreparation, administration, and storage of the medication placenta accreta methotrexate.
• Do not take more of this medication than is prescribed placenta accreta methotrexate. Too much methotrexatecan be dangerous, possibly resulting in death placenta accreta methotrexate. Methotrexate is used to treatdifferent medical conditions, each with a different dosing regimen placenta accreta methotrexate. Follow yourdoctor's instructions placenta accreta methotrexate.
• It is important to take methotrexate regularly to get the most benefit placenta accreta methotrexate.
• Your doctor may want you to have blood tests or other medical evaluationsduring treatment with methotrexate to monitor progress and side effects placenta accreta methotrexate.
• Store methotrexate at room temperature away from moisture and heat placenta accreta methotrexate.
What happens if I miss a dose?
• Contact your doctor if you miss a dose of methotrexate placenta accreta methotrexate.
What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected placenta accreta methotrexate.
• Symptoms of a methotrexate overdose may include nausea, vomiting, bleedingin the stomach, sores in the mouth, blood and bone marrow problems, and possiblydeath placenta accreta methotrexate.
What should I avoid while taking methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor placenta accreta methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects placenta accreta methotrexate. Discuss the use of aspirin and NSAIDs with yourdoctor placenta accreta methotrexate.
• Do not drink alcohol while taking methotrexate placenta accreta methotrexate.
• Avoid prolonged exposure to sunlight placenta accreta methotrexate. Methotrexate may increase the sensitivityof the skin to sunlight placenta accreta methotrexate. Use a sunscreen and wear protective clothing when exposureto the sun is unavoidable placenta accreta methotrexate.
What are the possible side effects of methotrexate?
• Methotrexate may cause side effects that could be dangerous or life-threatening placenta accreta methotrexate. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment placenta accreta methotrexate. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain); sores in or aroundthe mouth; liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others placenta accreta methotrexate. Notify your doctor immediately if you develop any of these symptoms placenta accreta methotrexate.
• If you experience any of the following serious side effects, seek emergencymedical attention or contact your doctor immediately:
· an allergic reaction (shortness of breath; closing of the throat; difficultybreathing; swelling of the lips, face, or tongue; or hives);
· joint pain; or
· confusion, unusual behavior, or seizures placenta accreta methotrexate.
• Other, less serious side effects may be more likely to occur placenta accreta methotrexate. Continueto take methotrexate and notify your doctor if you experience
· nausea, vomiting, or decreased appetite;
· itching or a skin rash;
· hair loss;
· boils or acne;
· dizziness;
· increased sensitivity of the skin to sunlight;
· headache;
· drowsiness; or
· blurred vision placenta accreta methotrexate.
• Side effects other than those listed here may also occur placenta accreta methotrexate. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome placenta accreta methotrexate.
What other drugs will affect methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor placenta accreta methotrexate. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects placenta accreta methotrexate.
• Before taking methotrexate, tell your doctor if you are taking any ofthe following medicines:
· etretinate (Tegison);
· acitretin (Soriatane);
· theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin,others);
· phenytoin (Dilantin);
· probenecid (Benemid);
· procarbazine (Matulane);
· folic acid or a vitamin supplement that contains folic acid;
· a penicillin antibiotic such as ampicillin (Principen, others), amoxicillin(Amoxil, Trimox, Augmentin, others), dicloxacillin (Dynapen, others), penicillin(Pen-Vee-K, Veetids, others), and others;
· a tetracycline antibiotic such as minocycline (Minocin, Dynacin, others),doxycycline (Vibramycin, Vibra-Tabs, others), tetracycline (Sumycin, others),and others; or
· a sulfa-based medicine such as sulfamethoxazole (Bactrim, Septra, Sulfatrim,Gantanol), sulfisoxazole (Gantrisin), and others placenta accreta methotrexate.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring if you are taking any of the medicines listedabove placenta accreta methotrexate.
• Drugs other than those listed here may also interact with methotrexate placenta accreta methotrexate. Talk to your doctor and pharmacist before taking any prescription or over-the-countermedicines, including vitamins, minerals, and herbal products placenta accreta methotrexate.
Where can I get more information?
• Your pharmacist has additional information about methotrexate writtenfor health professionals that you may read placenta accreta methotrexate.
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