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ttc after methotrexate shot
(meth oh TREX ate)
Dose Pack, Trexall

What is the most important information I should know about methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication ttc after methotrexate shot.
• Methotrexate may cause side effects that could be dangerous or life-threatening ttc after methotrexate shot. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment ttc after methotrexate shot. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain, sores in or aroundthe mouth); liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others ttc after methotrexate shot. Notify your doctor immediately if you develop any of these symptoms ttc after methotrexate shot.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment ttc after methotrexate shot. Methotrexate is in the FDA pregnancy category X ttc after methotrexate shot. This meansthat it is known to cause birth defects in an unborn baby ttc after methotrexate shot. Methotrexate canaffect a baby both when a woman is treated and when a man is treated ttc after methotrexate shot. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment ttc after methotrexate shot. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment ttc after methotrexate shot.
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor ttc after methotrexate shot. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects ttc after methotrexate shot. Discuss the use of aspirin and NSAIDs with yourdoctor ttc after methotrexate shot.
• Do not drink alcohol while taking methotrexate ttc after methotrexate shot.


What is methotrexate?
• Methotrexate interferes with the production and maintenance of DNA, whichis the genetic material in the cells of the body ttc after methotrexate shot. Methotrexate has a greatereffect on cells that reproduce often such as cancer cells, bone marrow cells,skin cells, and others ttc after methotrexate shot. This is how methotrexate works in the treatment of cancerand psoriasis ttc after methotrexate shot. It is not known exactly how methotrexate works in the treatmentof rheumatoid arthritis ttc after methotrexate shot.
• Methotrexate is used to treat certain types of cancer, psoriasis, andrheumatoid arthritis ttc after methotrexate shot.
• Methotrexate may also be used for purposes other than those listed inthis medication guide ttc after methotrexate shot.


What should I discuss with my healthcare provider before taking methotrexate?
• Before taking methotrexate, tell your doctor if you have
· liver disease or a history of liver problems;
· kidney disease;
· alcoholism or alcoholic liver disease;
· an immune system disorder;
· blood or bone marrow problems;
· an infection;
· a stomach ulcer;
· ulcerative colitis;
· diabetes;
· fluid around the lungs or in the abdomen; or
· asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis,or any other lung disease ttc after methotrexate shot.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring during therapy if you have any of the conditionslisted above ttc after methotrexate shot.
• Do not take methotrexate if you are pregnant or could become pregnantduring treatment ttc after methotrexate shot. Methotrexate is in the FDA pregnancy category X ttc after methotrexate shot. This meansthat it is known to cause birth defects in an unborn baby ttc after methotrexate shot. Methotrexate canaffect a baby both when a woman is treated and when a man is treated ttc after methotrexate shot. If thewoman is being treated with methotrexate, pregnancy must be avoided during treatmentand for one ovulatory cycle following treatment ttc after methotrexate shot. If the man is being treatedwith methotrexate, pregnancy must be avoided during treatment and for 3 monthsfollowing treatment ttc after methotrexate shot.
• Methotrexate may be harmful to a nursing infant ttc after methotrexate shot. Breast-feeding is notrecommended during treatment with methotrexate ttc after methotrexate shot.


How should I take methotrexate?
• Methotrexate should only be administered under the supervision of a qualifiedhealthcare provider experienced in the use of this medication ttc after methotrexate shot.
• Take oral methotrexate exactly as directed by your doctor ttc after methotrexate shot. If you donot understand these instructions, ask your pharmacist, nurse, or doctor toexplain them to you ttc after methotrexate shot.
• Take each oral dose with a full glass of water ttc after methotrexate shot.
• Methotrexate is also available as an injection ttc after methotrexate shot. If you are using injectablemethotrexate at home, your doctor will give you detailed instructions regardingpreparation, administration, and storage of the medication ttc after methotrexate shot.
• Do not take more of this medication than is prescribed ttc after methotrexate shot. Too much methotrexatecan be dangerous, possibly resulting in death ttc after methotrexate shot. Methotrexate is used to treatdifferent medical conditions, each with a different dosing regimen ttc after methotrexate shot. Follow yourdoctor's instructions ttc after methotrexate shot.
• It is important to take methotrexate regularly to get the most benefit ttc after methotrexate shot.
• Your doctor may want you to have blood tests or other medical evaluationsduring treatment with methotrexate to monitor progress and side effects ttc after methotrexate shot.
• Store methotrexate at room temperature away from moisture and heat ttc after methotrexate shot.


What happens if I miss a dose?
• Contact your doctor if you miss a dose of methotrexate ttc after methotrexate shot.


What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected ttc after methotrexate shot.
• Symptoms of a methotrexate overdose may include nausea, vomiting, bleedingin the stomach, sores in the mouth, blood and bone marrow problems, and possiblydeath ttc after methotrexate shot.


What should I avoid while taking methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor ttc after methotrexate shot. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects ttc after methotrexate shot. Discuss the use of aspirin and NSAIDs with yourdoctor ttc after methotrexate shot.
• Do not drink alcohol while taking methotrexate ttc after methotrexate shot.
• Avoid prolonged exposure to sunlight ttc after methotrexate shot. Methotrexate may increase the sensitivityof the skin to sunlight ttc after methotrexate shot. Use a sunscreen and wear protective clothing when exposureto the sun is unavoidable ttc after methotrexate shot.


What are the possible side effects of methotrexate?
• Methotrexate may cause side effects that could be dangerous or life-threatening ttc after methotrexate shot. Discuss with your doctor the risks and benefits of using methotrexate beforestarting treatment ttc after methotrexate shot. Methotrexate has been reported to cause blood and bone marrowproblems (fever, chills, sore throat, unusual bruising or bleeding, black, bloodyor tarry stools,); lung problems (unexplained shortness of breath, coughing,or wheezing); stomach problems (diarrhea, abdominal pain); sores in or aroundthe mouth; liver problems (yellow skin or eyes, unusual fatigue); kidney problems(blood in the urine; darkened urine, swelling of the feet or legs); and others ttc after methotrexate shot. Notify your doctor immediately if you develop any of these symptoms ttc after methotrexate shot.
• If you experience any of the following serious side effects, seek emergencymedical attention or contact your doctor immediately:
· an allergic reaction (shortness of breath; closing of the throat; difficultybreathing; swelling of the lips, face, or tongue; or hives);
· joint pain; or
· confusion, unusual behavior, or seizures ttc after methotrexate shot.
• Other, less serious side effects may be more likely to occur ttc after methotrexate shot. Continueto take methotrexate and notify your doctor if you experience
· nausea, vomiting, or decreased appetite;
· itching or a skin rash;
· hair loss;
· boils or acne;
· dizziness;
· increased sensitivity of the skin to sunlight;
· headache;
· drowsiness; or
· blurred vision ttc after methotrexate shot.
• Side effects other than those listed here may also occur ttc after methotrexate shot. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome ttc after methotrexate shot.


What other drugs will affect methotrexate?
• Do not take aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen (Advil, Motrin, Nuprin, others), ketoprofen (Orudis KT, Orudis,Oruvail), naproxen (Aleve, Naprosyn, Anaprox), and others except under the directionof your doctor ttc after methotrexate shot. Although these medications may be prescribed together to treatcertain conditions, methotrexate may interact with aspirin and NSAIDs, and possiblycause serious side effects ttc after methotrexate shot.
• Before taking methotrexate, tell your doctor if you are taking any ofthe following medicines:
· etretinate (Tegison);
· acitretin (Soriatane);
· theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin,others);
· phenytoin (Dilantin);
· probenecid (Benemid);
· procarbazine (Matulane);
· folic acid or a vitamin supplement that contains folic acid;
· a penicillin antibiotic such as ampicillin (Principen, others), amoxicillin(Amoxil, Trimox, Augmentin, others), dicloxacillin (Dynapen, others), penicillin(Pen-Vee-K, Veetids, others), and others;
· a tetracycline antibiotic such as minocycline (Minocin, Dynacin, others),doxycycline (Vibramycin, Vibra-Tabs, others), tetracycline (Sumycin, others),and others; or
· a sulfa-based medicine such as sulfamethoxazole (Bactrim, Septra, Sulfatrim,Gantanol), sulfisoxazole (Gantrisin), and others ttc after methotrexate shot.
• You may not be able to take methotrexate, or you may require a dosageadjustment or special monitoring if you are taking any of the medicines listedabove ttc after methotrexate shot.
• Drugs other than those listed here may also interact with methotrexate ttc after methotrexate shot. Talk to your doctor and pharmacist before taking any prescription or over-the-countermedicines, including vitamins, minerals, and herbal products ttc after methotrexate shot.


Where can I get more information?
• Your pharmacist has additional information about methotrexate writtenfor health professionals that you may read ttc after methotrexate shot.


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