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drug morphine synapse
(MOR feen)
Kadian, MS Contin, MSIR, OMS, Oramorph SR, Rescudose, RMS, Roxanol, Roxanol 100,Roxanol-T

What is the most important information I should know about morphine?
• Do not stop taking morphine suddenly if you have been taking it continuouslyfor more than 5 to 7 days drug morphine synapse. Stopping suddenly could cause withdrawal symptomsand make you very uncomfortable drug morphine synapse. Your doctor may want to gradually reduce yourdose drug morphine synapse.
• Do not crush, chew, break, or open controlled-release forms of morphinesuch as Oramorph SR, Kadian, and MS Contin drug morphine synapse. Swallow them whole drug morphine synapse. They are speciallyformulated to release morphine slowly into your system drug morphine synapse. Breaking them wouldcause too much of the drug to be released into your blood at one time drug morphine synapse.
• Morphine will cause drowsiness and fatigue drug morphine synapse. Avoid alcohol, sleeping pills,antihistamines, sedatives, and tranquilizers that may also make you drowsy exceptunder the supervision of your doctor drug morphine synapse.
• Morphine will also cause constipation drug morphine synapse. Drink plenty of water (six toeight full glasses a day) to lessen this side effect drug morphine synapse. Increasing the amountof fiber in your diet can also help to alleviate constipation drug morphine synapse.
• Never take more morphine than is prescribed for you drug morphine synapse. If your pain isnot being adequately treated, talk to your doctor drug morphine synapse.


What is morphine?
• Morphine is in a class of drugs called narcotic analgesics drug morphine synapse. It relievespain drug morphine synapse.
• Morphine is used to treat moderate-to-severe pain drug morphine synapse.
• Morphine may also be used for purposes other than those listed in thismedication guide drug morphine synapse.


Who should not take morphine?
• Morphine is habit forming and should only be used under close supervisionif you have an alcohol or drug addiction drug morphine synapse.
• Before taking this medication, tell your doctor if you have
· kidney disease,
· liver disease,
· asthma,
· urinary retention,
· an enlarged prostate,
· hypothyroidism,
· seizures or epilepsy,
· gallbladder disease,
· a head injury, or
· Addison's disease drug morphine synapse.
• You may not be able to take morphine, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove drug morphine synapse.
• Morphine may cause addiction and withdrawal symptoms as well as otherharmful effects in an unborn baby drug morphine synapse. Do not take morphine without first talkingto your doctor if you are pregnant drug morphine synapse.
• Morphine may also cause addiction and withdrawal symptoms in a nursinginfant drug morphine synapse. Do not take morphine without first talking to your doctor if you arebreast-feeding a baby drug morphine synapse.
• If you are younger than 18 years of age or older than 60 years of age,you may be more likely to experience side effects from morphine therapy drug morphine synapse. Useextra caution drug morphine synapse.


How should I take morphine?
• Take morphine exactly as directed by your doctor drug morphine synapse. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you drug morphine synapse.
• Take each dose with a full glass of water drug morphine synapse.
• Take morphine with food or milk if it upsets your stomach drug morphine synapse.
• Never take more of this medication than is prescribed for you drug morphine synapse. Too muchmorphine could be very harmful drug morphine synapse.
• To ensure that you get a correct dose, measure the liquid form of morphinewith a special dose-measuring spoon or cup, not with a regular tablespoon drug morphine synapse. Ifyou do not have a dose-measuring device, ask your pharmacist where you can getone drug morphine synapse.
• Do not crush, chew, break, or open controlled-release forms of morphinesuch as Oramorph SR, Kadian, or MS Contin drug morphine synapse. Swallow them whole drug morphine synapse. They are speciallyformulated to release morphine slowly into your system drug morphine synapse. Breaking them wouldcause too much drug to be released into your blood at one time drug morphine synapse.
• Use the suppositories rectally as directed by your doctor drug morphine synapse. If you donot know how to use them, ask you doctor, nurse, or pharmacist for instructions drug morphine synapse.
• Do not stop taking morphine suddenly if you have been taking it continuouslyfor more than 5 to 7 days drug morphine synapse. Stopping suddenly could cause withdrawal symptomsand make you feel uncomfortable drug morphine synapse. Your doctor may want to gradually reduce yourdose drug morphine synapse.
• Morphine will cause constipation drug morphine synapse. Increase the amount of fiber and water(at least six to eight full glasses daily) in your diet to prevent constipation drug morphine synapse.
• Do not share this medication with anyone else drug morphine synapse.
• Store morphine at room temperature away from moisture and heat drug morphine synapse.
• Discard any opened bottle of morphine solution after 90 days drug morphine synapse.


What happens if I miss a dose?
• Take the missed dose as soon as you remember drug morphine synapse. Do not take a double doseof this medication drug morphine synapse. Wait the prescribed amount of time before taking your nextdose drug morphine synapse.


What happens if I overdose?
• Seek emergency medical attention drug morphine synapse.
• Symptoms of a morphine overdose include slow breathing, seizures, dizziness,weakness, loss of consciousness, coma, confusion, tiredness, cold and clammyskin, and small pupils drug morphine synapse.


What should I avoid while taking morphine?
• Avoid alcohol while taking morphine drug morphine synapse. Alcohol will greatly increase thedrowsiness and dizziness caused by morphine and could be dangerous drug morphine synapse.
• Also avoid sleeping pills, tranquilizers, sedatives, and antihistaminesexcept under the supervision of your doctor drug morphine synapse. These medications also may causedangerous sedation drug morphine synapse.
• Use caution when driving, operating machinery, or performing other hazardousactivities drug morphine synapse. Morphine may cause drowsiness drug morphine synapse. If you experience drowsiness, avoidthese activities drug morphine synapse.


What are the possible side effects of morphine?
• If you experience any of the following serious side effects, stop takingmorphine and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· slow, weak breathing;
· seizures;
· cold, clammy skin;
· severe weakness or dizziness; or
· unconsciousness drug morphine synapse.
• Other, less serious side effects may be more likely to occur drug morphine synapse. Continueto take morphine and talk to your doctor if you experience
· constipation;
· dry mouth, nausea, vomiting, or decreased appetite;
· dizziness, tiredness, or lightheadedness;
· muscle twitches;
· sweating;
· itching;
· decreased urination; or
· decreased sex drive drug morphine synapse.
• Morphine is habit forming drug morphine synapse. Do not stop taking it suddenly drug morphine synapse.
• Side effects other than those listed here may also occur drug morphine synapse. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome drug morphine synapse.


What other drugs will affect morphine?
• Do not take morphine if you have taken a monoamine oxidase inhibitor(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine(Parnate) in the last 14 days drug morphine synapse. Dangerous side effects could result drug morphine synapse.
• The most serious interactions affecting morphine are with those drugsthat also cause sedation drug morphine synapse. The following drugs may lead to dangerous sedationif taken with morphine:
· antihistamines such as brompheniramine (Dimetane, Bromfed, others),diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton,Teldrin, others), and others;
· tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin(Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline(Zoloft), and paroxetine (Paxil);
· other commonly used antidepressants, including amoxapine (Asendin),clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline(Pamelor), and protriptyline (Vivactil);
· anticholinergics such as belladonna (Donnatal), clidinium (Quarzan),dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent),propantheline (Pro-Banthine), and scopolamine (Transderm-Scop);
· phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin),thioridazine (Mellaril), and prochlorperazine (Compazine); and
· tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal),amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium),lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril) drug morphine synapse.
• Do not take any of the drugs listed above without the approval of yourdoctor drug morphine synapse.
• Drugs other than those listed here may also interact with morphine drug morphine synapse. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines drug morphine synapse.


Where can I get more information?
• Your pharmacist has additional information about morphine written forhealth professionals that you may read drug morphine synapse.


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