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making morphine
(MOR feen)
Kadian, MS Contin, MSIR, OMS, Oramorph SR, Rescudose, RMS, Roxanol, Roxanol 100,Roxanol-T

What is the most important information I should know about morphine?
• Do not stop taking morphine suddenly if you have been taking it continuouslyfor more than 5 to 7 days making morphine. Stopping suddenly could cause withdrawal symptomsand make you very uncomfortable making morphine. Your doctor may want to gradually reduce yourdose making morphine.
• Do not crush, chew, break, or open controlled-release forms of morphinesuch as Oramorph SR, Kadian, and MS Contin making morphine. Swallow them whole making morphine. They are speciallyformulated to release morphine slowly into your system making morphine. Breaking them wouldcause too much of the drug to be released into your blood at one time making morphine.
• Morphine will cause drowsiness and fatigue making morphine. Avoid alcohol, sleeping pills,antihistamines, sedatives, and tranquilizers that may also make you drowsy exceptunder the supervision of your doctor making morphine.
• Morphine will also cause constipation making morphine. Drink plenty of water (six toeight full glasses a day) to lessen this side effect making morphine. Increasing the amountof fiber in your diet can also help to alleviate constipation making morphine.
• Never take more morphine than is prescribed for you making morphine. If your pain isnot being adequately treated, talk to your doctor making morphine.


What is morphine?
• Morphine is in a class of drugs called narcotic analgesics making morphine. It relievespain making morphine.
• Morphine is used to treat moderate-to-severe pain making morphine.
• Morphine may also be used for purposes other than those listed in thismedication guide making morphine.


Who should not take morphine?
• Morphine is habit forming and should only be used under close supervisionif you have an alcohol or drug addiction making morphine.
• Before taking this medication, tell your doctor if you have
· kidney disease,
· liver disease,
· asthma,
· urinary retention,
· an enlarged prostate,
· hypothyroidism,
· seizures or epilepsy,
· gallbladder disease,
· a head injury, or
· Addison's disease making morphine.
• You may not be able to take morphine, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove making morphine.
• Morphine may cause addiction and withdrawal symptoms as well as otherharmful effects in an unborn baby making morphine. Do not take morphine without first talkingto your doctor if you are pregnant making morphine.
• Morphine may also cause addiction and withdrawal symptoms in a nursinginfant making morphine. Do not take morphine without first talking to your doctor if you arebreast-feeding a baby making morphine.
• If you are younger than 18 years of age or older than 60 years of age,you may be more likely to experience side effects from morphine therapy making morphine. Useextra caution making morphine.


How should I take morphine?
• Take morphine exactly as directed by your doctor making morphine. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you making morphine.
• Take each dose with a full glass of water making morphine.
• Take morphine with food or milk if it upsets your stomach making morphine.
• Never take more of this medication than is prescribed for you making morphine. Too muchmorphine could be very harmful making morphine.
• To ensure that you get a correct dose, measure the liquid form of morphinewith a special dose-measuring spoon or cup, not with a regular tablespoon making morphine. Ifyou do not have a dose-measuring device, ask your pharmacist where you can getone making morphine.
• Do not crush, chew, break, or open controlled-release forms of morphinesuch as Oramorph SR, Kadian, or MS Contin making morphine. Swallow them whole making morphine. They are speciallyformulated to release morphine slowly into your system making morphine. Breaking them wouldcause too much drug to be released into your blood at one time making morphine.
• Use the suppositories rectally as directed by your doctor making morphine. If you donot know how to use them, ask you doctor, nurse, or pharmacist for instructions making morphine.
• Do not stop taking morphine suddenly if you have been taking it continuouslyfor more than 5 to 7 days making morphine. Stopping suddenly could cause withdrawal symptomsand make you feel uncomfortable making morphine. Your doctor may want to gradually reduce yourdose making morphine.
• Morphine will cause constipation making morphine. Increase the amount of fiber and water(at least six to eight full glasses daily) in your diet to prevent constipation making morphine.
• Do not share this medication with anyone else making morphine.
• Store morphine at room temperature away from moisture and heat making morphine.
• Discard any opened bottle of morphine solution after 90 days making morphine.


What happens if I miss a dose?
• Take the missed dose as soon as you remember making morphine. Do not take a double doseof this medication making morphine. Wait the prescribed amount of time before taking your nextdose making morphine.


What happens if I overdose?
• Seek emergency medical attention making morphine.
• Symptoms of a morphine overdose include slow breathing, seizures, dizziness,weakness, loss of consciousness, coma, confusion, tiredness, cold and clammyskin, and small pupils making morphine.


What should I avoid while taking morphine?
• Avoid alcohol while taking morphine making morphine. Alcohol will greatly increase thedrowsiness and dizziness caused by morphine and could be dangerous making morphine.
• Also avoid sleeping pills, tranquilizers, sedatives, and antihistaminesexcept under the supervision of your doctor making morphine. These medications also may causedangerous sedation making morphine.
• Use caution when driving, operating machinery, or performing other hazardousactivities making morphine. Morphine may cause drowsiness making morphine. If you experience drowsiness, avoidthese activities making morphine.


What are the possible side effects of morphine?
• If you experience any of the following serious side effects, stop takingmorphine and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· slow, weak breathing;
· seizures;
· cold, clammy skin;
· severe weakness or dizziness; or
· unconsciousness making morphine.
• Other, less serious side effects may be more likely to occur making morphine. Continueto take morphine and talk to your doctor if you experience
· constipation;
· dry mouth, nausea, vomiting, or decreased appetite;
· dizziness, tiredness, or lightheadedness;
· muscle twitches;
· sweating;
· itching;
· decreased urination; or
· decreased sex drive making morphine.
• Morphine is habit forming making morphine. Do not stop taking it suddenly making morphine.
• Side effects other than those listed here may also occur making morphine. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome making morphine.


What other drugs will affect morphine?
• Do not take morphine if you have taken a monoamine oxidase inhibitor(MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine(Parnate) in the last 14 days making morphine. Dangerous side effects could result making morphine.
• The most serious interactions affecting morphine are with those drugsthat also cause sedation making morphine. The following drugs may lead to dangerous sedationif taken with morphine:
· antihistamines such as brompheniramine (Dimetane, Bromfed, others),diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton,Teldrin, others), and others;
· tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin(Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline(Zoloft), and paroxetine (Paxil);
· other commonly used antidepressants, including amoxapine (Asendin),clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline(Pamelor), and protriptyline (Vivactil);
· anticholinergics such as belladonna (Donnatal), clidinium (Quarzan),dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent),propantheline (Pro-Banthine), and scopolamine (Transderm-Scop);
· phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin),thioridazine (Mellaril), and prochlorperazine (Compazine); and
· tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal),amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium),lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril) making morphine.
• Do not take any of the drugs listed above without the approval of yourdoctor making morphine.
• Drugs other than those listed here may also interact with morphine making morphine. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines making morphine.


Where can I get more information?
• Your pharmacist has additional information about morphine written forhealth professionals that you may read making morphine.


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