effects of motrin on the liver

What is the most important information I should know about Motrin?
• Take Motrin with food, milk, or an antacid to lessen stomach upset effects of motrin on the liver.
• Watch for bloody, black, or tarry stools or blood in the vomit effects of motrin on the liver. Thesesymptoms could indicate damage to the gastrointestinal tract effects of motrin on the liver.
• If you drink more than three alcoholic beverages a day, Motrin may increasethe risk of stomach bleeding effects of motrin on the liver.

What is Motrin?
• Motrin is in a class of drugs called nonsteroidal anti-inflammatory drugs(NSAIDs) effects of motrin on the liver. Motrin works by reducing hormones that cause inflammation and painin the body effects of motrin on the liver.
• Motrin is used to reduce the fever, pain, inflammation, and stiffnesscaused by many conditions, such as osteoarthritis, rheumatoid arthritis, andabdominal cramps associated with menstruation effects of motrin on the liver.
• Motrin may also be used for purposes other than those listed in thismedication guide effects of motrin on the liver.

Who should not take Motrin?
• Before taking this medication, tell your doctor if you
· have an allergy to aspirin or any other NSAIDs,
· have an ulcer or bleeding in the stomach,
· drink more than three alcoholic beverages a day,
· have liver or kidney disease,
· have a coagulation (bleeding or blood clotting) disorder,
· have congestive heart failure,
· have fluid retention,
· have heart disease, or
· have high blood pressure effects of motrin on the liver.
• You may not be able to take Motrin, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove effects of motrin on the liver.
• It is not known whether Motrin will harm an unborn baby effects of motrin on the liver. Motrin shouldnot be taken late in pregnancy (the third trimester) because a similar drugis known to affect the baby's heart effects of motrin on the liver. Do not take Motrin without first talkingto your doctor if you are pregnant effects of motrin on the liver.
• Motrin passes into breast milk in very small amounts, however it is notexpected to harm a nursing baby effects of motrin on the liver. Talk to your doctor before taking Motrin ifyou are breast-feeding effects of motrin on the liver.

How should I take Motrin?
• Take Motrin exactly as directed by your doctor effects of motrin on the liver. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you
• Take each dose with a full glass of water effects of motrin on the liver.
• Take Motrin with food, milk, or an antacid to lessen stomach upset effects of motrin on the liver.
• Store Motrin at room temperature away from moisture and heat effects of motrin on the liver.

What happens if I miss a dose?
• Take the missed dose as soon as you remember up to 2 hours late effects of motrin on the liver. If morethan 2 hours have passed since the missed dose, skip it and take only the nextregularly scheduled dose effects of motrin on the liver. Do not take a double dose effects of motrin on the liver.

What happens if I overdose?
• Seek emergency medical attention effects of motrin on the liver.
• Symptoms of a Motrin overdose include nausea, vomiting or stomach pain,dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures,sweating, numbness or tingling, little or no urine production, and slow breathing effects of motrin on the liver.

What should I avoid while taking Motrin?
• Avoid prolonged exposure to sunlight effects of motrin on the liver. Motrin may increase the sensitivityof the skin to sunlight effects of motrin on the liver. Use a sunscreen and wear protective clothing when exposureto the sun is unavoidable effects of motrin on the liver.
• If you drink more than three alcoholic beverages a day, Motrin may increasethe risk of stomach bleeding effects of motrin on the liver.

What are the possible side effects of Motrin?
• If you experience any of the following serious side effects, stop takingMotrin and seek medical treatment or call your doctor immediately:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· muscle cramps, numbness, or tingling;
· ulcers (open sores) in the mouth;
· rapid weight gain (fluid retention);
· seizures;
· black, bloody, or tarry stools;
· blood in your urine or vomit;
· decreased hearing or ringing in the ears;
· jaundice (yellowing of the skin or eyes); or
· abdominal cramping, indigestion, or heartburn effects of motrin on the liver.
• Other, less serious side effects may be more likely to occur effects of motrin on the liver. Continueto take Motrin and talk to your doctor if you experience
· dizziness or headache;
· nausea, gaseousness, diarrhea, or constipation;
· depression;
· fatigue or weakness;
· dry mouth; or
· irregular menstrual periods effects of motrin on the liver.
• Side effects other than those listed here may also occur effects of motrin on the liver. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome effects of motrin on the liver.

What other drugs will affect Motrin?
• Other prescription and over-the-counter drugs may increase the effectsof Motrin and cause dangerous side effects effects of motrin on the liver. Tell your doctor if you are takingany of the following drugs:
· another nonsteroidal anti-inflammatory drug (NSAID) such as ketoprofen(Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Aleve, Anaprox), diclofenac(Voltaren, Cataflam), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid),indomethacin (Indocin), ketorolac (Toradol), nabumetone (Relafen), oxaprozin(Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
· aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid),choline salicylate, and magnesium salicylate;
· a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril,others), chlorothiazide (Diuril, others), chlorthalidone (Thalitone), bumetanide(Bumex), ethacrynic acid (Edecrin), furosemide (Lasix), spironolactone (Aldactone),and amiloride (Midamor);
· an anticoagulant such as warfarin (Coumadin);
· a steroid such as prednisone (Deltasone);
· an oral diabetes medication such as glipizide (Glucotrol) or glyburide(Micronase, Diabeta); or
· lithium (Eskalith, Lithobid, others) effects of motrin on the liver.
• Talk to your doctor before taking Motrin if you are taking any othermedicines, especially any of the ones listed above effects of motrin on the liver.
• Drugs other than those listed here may also interact with Motrin effects of motrin on the liver. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines, including herbal products effects of motrin on the liver.

Where can I get more information?
• Your pharmacist has additional information about Motrin written for healthprofessionals that you may read effects of motrin on the liver.

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